Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153041 | 0.86 | ALDH1A1 (0.33) | GAA | |
| SCHEMBL3640338 | 0.84 | GSK3B (0.39) | GAA | |
| SCHEMBL5929376 | 0.83 | L3MBTL1 (0.31) | — | |
| SCHEMBL5929431 | 0.80 | PDE7A (0.41) | — | |
| SCHEMBL6839193 | 0.74 | ALDH1A1 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5929398 | 0.72 | GAA (0.32) | GAAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5767466 | 0.72 | NR3C1 (0.32) | — | |
| SCHEMBL2429219 | 0.70 | ADAM17 (0.32) | — | |
| SCHEMBL16592262 | 0.69 | — | — | |
| SCHEMBL343189 | 0.69 | FFAR4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329634-B2 | 3-Phenyl substituted 3-substituted-4ketolactams and ketolactones | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329634-B2 | 3-Phenyl substituted 3-substituted-4ketolactams and ketolactones | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | disclosed |
| US-20060094773-A1 | 3-Phenyl substituted 3-substituted-4ketolactams and ketolactones | BAYER CROPSCIENCE AG (DE) | 2006-05-04 | — | — | US | disclosed |
| EP-1587786-A1 | 2.4-DIHALOGEN-6-(C sb 2 /sb -C sb 3 /sb -ALKYL)-PHENYL SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004065366-A1 | 2.4-DIHALOGEN-6-(C2-C3-ALKYL)-PHENYL SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094773-A1 | 3-Phenyl substituted 3-substituted-4ketolactams and ketolactones | PKM, PDHX, KHK | GAA 312/4885GRIN2D 2076/4885GRIN3B 1792/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | GAA 124/4885GRIN2D 1032/4885GRIN3B 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.