Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363704 | 0.89 | — | — | |
| SCHEMBL363061 | 0.79 | KCNN4 (0.34) | MAPK1 | |
| SCHEMBL364429 | 0.79 | LDHA (0.36) | MAPK1 | |
| SCHEMBL362081 | 0.78 | HSD17B1 (0.33) | ALDH1A1 | |
| SCHEMBL364943 | 0.78 | — | — | |
| SCHEMBL363549 | 0.77 | NPC1 (0.34) | ALDH1A1MAPK1CYP2C19CYP2C9 | |
| SCHEMBL364193 | 0.77 | NPC1 (0.34) | ALDH1A1MAPK1CYP2C19CYP2C9 | |
| SCHEMBL363211 | 0.77 | NPC1 (0.34) | ALDH1A1MAPK1CYP2C19CYP2C9 | |
| SCHEMBL365152 | 0.75 | PTPN1 (0.33) | — | |
| SCHEMBL363769 | 0.75 | PTPN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |