SCHEMBL364086

SCHEMBL364086

Cl[Si](Cl)(Cl)CCC1CC=CCC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CDK1 P06493 2/20 0.31
CCNB1 P14635 2/20 0.31
CCNA2 P20248 2/20 0.31
CDK2 P24941 2/20 0.31
CCNA1 P78396 2/20 0.31
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20473662 0.88 KDM4E (0.31) KDM4EHSD17B10CDK1CCNB1CCNA2
SCHEMBL2101519 0.84 MAPK1 (0.32) KDM4EMAPK1ALDH1A1
SCHEMBL295809 0.84 MAOA (0.33) KDM4ECDK1CCNB1CCNA2CDK2
SCHEMBL17580303 0.79 ALDH1A1 (0.39) KDM4EHSD17B10CDK1CCNB1CCNA2
SCHEMBL9244041 0.77 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL12212529 0.76 KDM4E (0.34) KDM4EHSD17B10MAPK1ALDH1A1
SCHEMBL15703249 0.76 MAPK1 (0.35) KDM4ECDK1CCNB1CCNA2CDK2
SCHEMBL11276682 0.76
SCHEMBL8663830 0.75 KDM4E (0.31) KDM4EHSD17B10MAPK1ALDH1A1ALOX15
SCHEMBL2136195 0.75 MAPK1 (0.38) KDM4EHSD17B10CDK1CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3363821-B1 OLEFIN POLYMERIZATION CATALYST, PREPARATION METHOD THEREFOR, OLEFIN POLYMERIZATION CATALYST SYSTEM, APPLICATION THEREOF, AND PREPARATION METHOD FOR POLYOLEFIN RESIN INST CHEMISTRY CAS (CN) 2021-05-19 EP claimed
EP-3363822-B1 USE OF ORGANIC SILOXANE, AND POLYOLEFIN RESIN AND PREPARATION METHOD THEREOF INST CHEMISTRY CAS (CN) 2021-05-19 EP claimed
US-10934373-B2 Use of organosilane, and polyolefin resin and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-03-02 US claimed
US-10836846-B2 Olefin polymerization catalyst, preparation method thereof, olefin polymerization catalyst system, use thereof, and method of preparing polyolefin resin INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2020-11-17 US claimed
US-20180305477-A1 OLEFIN POLYMERIZATION CATALYST, PREPARATION METHOD THEREFOR, OLEFIN POLYMERIZATION CATALYST SYSTEM, APPLICATION THEREOF, AND PREPARATION METHOD FOR POLYOLEFIN RESIN INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-10-25 US claimed
US-20180298125-A1 USE OF ORGANOSILANE, AND POLYOLEFIN RESIN AND PREPARATION METHOD THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-10-18 US claimed
EP-3363822-A1 USE OF ORGANIC SILOXANE, AND POLYOLEFIN RESIN AND PREPARATION METHOD THEREOF Institute of Chemistry, Chinese Academy of Science (CN) 2018-08-22 EP claimed
EP-3363821-A1 OLEFIN POLYMERIZATION CATALYST, PREPARATION METHOD THEREFOR, OLEFIN POLYMERIZATION CATALYST SYSTEM, APPLICATION THEREOF, AND PREPARATION METHOD FOR POLYOLEFIN RESIN Institute of Chemistry, Chinese Academy of Science (CN) 2018-08-22 EP claimed
EP-1241190-B1 Rubber composite GOODYEAR TIRE & RUBBER (US) 2005-01-26 EP claimed
US-6797762-B2 ADDITIONAL POLYMERIZATION OF AT LEAST ONE CONJUGATED DIENE HYDROCARBONS ON THE SURFACE OF A SILANIZED FILLER THE GOODYEAR TIRE & RUBBER COMPANY 2004-09-28 US claimed
US-20030019554-A1 Rubber composite containing in situ formed filler reinforcement and article, such as a tire, having a component comprised thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-30 US claimed
EP-1241190-A1 Rubber composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-09-18 EP claimed
US-6331500-B1 SHAPE-SELECTIVE ADSORBENTS AND CATALYSTS MODULATED WITH CROSSLINKED SILOXY MONOMERS; MICROPOROSITY CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-12-18 US claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
WO-1999010277-A1 FUNCTIONALIZED MOLECULAR SIEVES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1999-03-04 WO claimed
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
EP-0346862-A2 Process to graft stereoregular polymers of branched, higher alpha-olefins and compositions thereof PHILLIPS PETROLEUM COMPANY (US) 1989-12-20 EP disclosed
US-4888394-A HEAT RESISTANCE, HYDROLYTIC STABILITY PHILLIPS PETROLEUM COMPANY (US) 1989-12-19 US disclosed
US-4038302-A DRYING PROPERTIES VEB CHEMIEWERK NUENCHRITZ (DT) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 KDM4E 915/4885HSD17B10 2455/4885CDK1 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.