Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363687 | 0.86 | POLB (0.36) | POLB | |
| SCHEMBL363897 | 0.85 | AR (0.36) | TRPA1AR | |
| SCHEMBL363591 | 0.77 | UHRF1 (0.35) | CHEK1NTRK1PIM1CDK2CSNK2A1 | |
| SCHEMBL364776 | 0.77 | POLB (0.35) | POLBCHEK1NTRK1PIM1CDK2 | |
| SCHEMBL363274 | 0.77 | NPC1 (0.35) | POLB | |
| SCHEMBL365534 | 0.77 | NPC1 (0.35) | POLB | |
| SCHEMBL364627 | 0.77 | NPC1 (0.35) | POLB | |
| SCHEMBL364473 | 0.76 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL364539 | 0.75 | POLB (0.32) | POLB | |
| SCHEMBL364836 | 0.75 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |