Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361971 | 0.85 | NR1H2 (0.37) | KCNN4MEN1KMT2AKIF11SMN1; SMN2 | |
| SCHEMBL364097 | 0.85 | TRPA1 (0.35) | ARTRPA1 | |
| SCHEMBL364575 | 0.76 | KCNN4 (0.40) | ARKCNN4SMARCA2SMARCA4KDM4C | |
| SCHEMBL364193 | 0.73 | NPC1 (0.34) | ARTLR7RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL363211 | 0.73 | NPC1 (0.34) | ARTLR7RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL363549 | 0.73 | NPC1 (0.34) | ARTLR7RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL371147 | 0.72 | SORT1 (0.34) | MEN1KMT2AMAOBSMN1; SMN2NPC1 | |
| SCHEMBL364536 | 0.72 | SORT1 (0.35) | CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10538155 | 0.71 | KIF11 (0.46) | KCNN4MEN1KMT2AKIF11MAOB | |
| SCHEMBL362869 | 0.71 | TRPV1 (0.38) | TLR7MEN1KMT2ARXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |