Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718030 | 0.83 | RAB9A (0.54) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL3642839 | 0.82 | MAPT (0.88) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL29944827 | 0.81 | L3MBTL1 (0.57) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7492161 | 0.78 | LMNA (0.55) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL14516655 | 0.78 | KCNQ3 (0.50) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL5784045 | 0.77 | PTPN1 (0.82) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL28958702 | 0.76 | HPGD (0.71) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7492014 | 0.76 | RAB9A (0.55) | RAB9AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL14339878 | 0.76 | KCNQ3 (0.57) | RAB9ASMN1; SMN2 | |
| SCHEMBL6815538 | 0.76 | CYP17A1 (0.49) | RAB9AMAPTLMNASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |