Mandelic Acid

Mandelic Acid

SCHEMBL3645

C1N2CN3CN1CN(C2)C3.O=C(O)C(O)c1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.75
MAPK1 P28482 1/20 0.75
SRC P12931 2/20 0.52
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
CYP2D6 P10635 2/20 0.46
HPGD P15428 1/20 0.46
GAA P10253 2/20 0.42
CYP2C9 P11712 1/20 0.41
HSD17B10 Q99714 1/20 0.41
BLM P54132 2/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL9747772 1.00 LMNA (0.75) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL388417 0.98 LMNA (0.72) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL5313046 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL29777368 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL21647917 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL255601 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL165161 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL1050 0.87 LMNA (1.00) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL29214389 0.85 LMNA (0.86) LMNAMAPK1SRCCES2CES1
Mandelic Acid SCHEMBL3622024 0.85 LMNA (0.86) LMNAMAPK1SRCCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4530 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
CN-119548497-A Method for treating myopia by using vinpocetine 温州医科大学附属眼视光医院 2025-03-04 CN claimed
EP-3197459-B1 POLYMERIC BILE ACID DERIVATIVES INHIBIT HEPATITIS B AND D VIRUS AND NTCP TRANSPORT HUAHUI HEALTH LTD (CN) 2025-02-12 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
CN-118634218-A Pharmaceutical composition for effectively delaying and treating myopia 温州医科大学附属眼视光医院 2024-09-13 CN claimed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 US claimed
EP-3965771-A1 FINISHED PHARMACEUTICAL DOSAGE FORM OF A METHENAMINE SALT SUCH AS METHENAMINE MANDELATE Edenbridge Pharmaceuticals, LLC (US) 2022-03-16 EP claimed
EP-3912989-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) 2021-11-24 EP claimed
US-20210322424-A1 Finished Pharmaceutical Dosage Form Of A Methenamine Salt Such As Methenamine Mandelate Edenbridge Pharmaceuticals, LLC (US) 2021-10-21 US claimed
WO-2021112914-A1 FINISHED PHARMACEUTICAL DOSAGE FORM OF A METHENAMINE SALT SUCH AS METHENAMINE MANDELATE Edenbridge Pharmaceuticals, LLC (US) 2021-06-10 WO claimed
EP-0436664-A1 CLEAVABLE LINKERS FOR THE REDUCTION OF NON-TARGET ORGAN RETENTION OF IMMUNOCONJUGATES. NEORX CORP (US) 1991-07-17 EP claimed
US-4952402-A EDIBLE TASTE-MASKED DRUGS; MICROMATRIX ACTIVE MATERIAL COATED WITH NONTOXIC POLYMER; LIQUIDS; TABLETS ELAN CORPORATION, P.L.C. (IE) 1990-08-28 US claimed
EP-0303545-A2 Process for the preparation of phenylethanolaminotetralines ELF SANOFI (FR) 1989-02-15 EP claimed
US-4601880-A POLYMER, FORMALDEHYDE RELEASING COMPOUND ALZA CORPORATION (US) 1986-07-22 US claimed
US-4464258-A METHENAMINE ALZA CORPORATION (US) 1984-08-07 US claimed
US-4369172-A Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose FOREST LABORATORIES INC. (US) 1983-01-18 US claimed
US-4288543-A SAMPLING IN LIQUID PHASE WITH ANTIGROWTH AGENTS-BIOLOGICAL PFIZER INC. (US) 1981-09-08 US claimed
US-4241195-A COATING OF FORMAMIDINESULFINIC ACID, METHENAMINE MANDELATE, IN RESINOUS CARRIER WESTINGHOUSE ELECTRIC CORP. (US) 1980-12-23 US claimed
US-4149161-A Protecting electrical apparatus with gas generating compounds WESTINGHOUSE ELECTRIC CORP. (US) 1979-04-10 US claimed
US-4126468-A Radiation sensitive compositions of quaternary ammonium salt and carboxylic acid sensitizer VICKERS LIMITED (GB) 1978-11-21 US claimed