Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL3645 | 1.00 | LMNA (0.75) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL388417 | 0.98 | LMNA (0.72) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL5313046 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL29777368 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL21647917 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL255601 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL165161 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL1050 | 0.87 | LMNA (1.00) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL29214389 | 0.85 | LMNA (0.86) | LMNAMAPK1SRCCES2CES1 | |
| Mandelic Acid SCHEMBL3622024 | 0.85 | LMNA (0.86) | LMNAMAPK1SRCCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171563-A | Cleavable linkers for the reduction of non-target organ retention of immunoconjugates | NEORX CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |