Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365547 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL365090 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL366922 | 0.76 | L3MBTL1 (0.62) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL364541 | 0.74 | KDM4E (1.00) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL365000 | 0.74 | HTT (0.42) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL367737 | 0.73 | L3MBTL1 (0.45) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL365640 | 0.71 | KMT2A (0.43) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL366758 | 0.71 | EGFR (0.46) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL366926 | 0.70 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL366888 | 0.70 | EGFR (0.44) | ALDH1A1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |