Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365090 | 0.78 | ALDH1A1 (0.68) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL366757 | 0.75 | ALDH1A1 (0.59) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL364542 | 0.71 | ALDH1A1 (0.59) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL366922 | 0.68 | L3MBTL1 (0.62) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL365547 | 0.66 | ALDH1A1 (0.45) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL367737 | 0.65 | L3MBTL1 (0.45) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL30319488 | 0.64 | PARP1 (0.42) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL364541 | 0.62 | KDM4E (1.00) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL150623 | 0.62 | ALDH1A1 (0.64) | EGFRSRCALDH1A1KDM4EMEN1 | |
| SCHEMBL29429129 | 0.62 | ALDH1A1 (0.64) | EGFRSRCALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |