Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121809 | 0.83 | GSK3A (0.40) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL1010815 | 0.83 | BRD4 (0.39) | KMT2AALDH1A1KDM4EMAPK1MEN1 | |
| SCHEMBL1268069 | 0.81 | ALDH1A1 (0.42) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL5480653 | 0.80 | PLA2G10 (0.40) | KMT2AALDH1A1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL23772924 | 0.78 | TDP1 (0.42) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL5653075 | 0.78 | ALDH1A1 (0.39) | GSK3AGSK3BELANEKMT2AALDH1A1 | |
| SCHEMBL1016674 | 0.77 | CHRM1 (0.42) | L3MBTL1MAPK1GAA | |
| SCHEMBL15618675 | 0.77 | CHRM1 (0.42) | L3MBTL1MAPK1GAA | |
| SCHEMBL7319111 | 0.77 | MAPK1 (0.47) | KMT2AALDH1A1KDM4EL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL23751634 | 0.77 | TDP1 (0.41) | GSK3AGSK3BABL1RIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176219-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009009550-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | WO | disclosed |