Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366072 | 0.92 | FFAR1 (0.37) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL365785 | 0.91 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL366015 | 0.90 | CYP11B1 (0.37) | ALDH1A1KMT2AKDM4EMEN1PDE4A | |
| SCHEMBL367248 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL367224 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EMEN1PLK1 | |
| SCHEMBL366564 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL364642 | 0.84 | CYP11B1 (0.40) | ALDH1A1KDM4EPDE4APDE4BPDE4C | |
| SCHEMBL367346 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL365102 | 0.83 | KDM4E (0.41) | ALDH1A1KMT2AKDM4EMEN1FFAR1 | |
| SCHEMBL365964 | 0.83 | KDM4E (0.36) | ALDH1A1KMT2AKDM4EMEN1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |