Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364640 | 0.92 | ALDH1A1 (0.39) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL366564 | 0.92 | ALDH1A1 (0.38) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL364642 | 0.91 | CYP11B1 (0.40) | ALDH1A1KDM4EFNTAFNTBPGGT1B | |
| SCHEMBL367346 | 0.90 | ALDH1A1 (0.37) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL365105 | 0.86 | ALDH1A1 (0.43) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL365102 | 0.85 | KDM4E (0.41) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL365785 | 0.84 | ALDH1A1 (0.38) | FFAR1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL367193 | 0.83 | GPR132 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL366015 | 0.83 | CYP11B1 (0.37) | ALDH1A1KMT2AKDM4EMEN1CYP19A1 | |
| SCHEMBL366830 | 0.82 | ALDH1A1 (0.35) | ALDH1A1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |