Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954109 | 0.84 | EGFR (0.36) | EGFR | |
| SCHEMBL1485098 | 0.79 | LIPE (0.35) | LRRK2 | |
| SCHEMBL31441573 | 0.79 | LIPE (0.35) | LRRK2 | |
| SCHEMBL20894750 | 0.77 | LPL (0.33) | EGFR | |
| SCHEMBL29537987 | 0.77 | LPL (0.33) | EGFR | |
| SCHEMBL8222751 | 0.74 | NOS3 (0.32) | EGFR | |
| SCHEMBL22616641 | 0.74 | LPL (0.38) | EGFR | |
| SCHEMBL27403756 | 0.70 | UCHL1 (0.34) | EGFR | |
| SCHEMBL18342697 | 0.69 | JAK2 (0.35) | EGFR | |
| SCHEMBL30836599 | 0.69 | JAK2 (0.35) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593432-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007861-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |