Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.32 |
| ▸ | S100A10 | P60903 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL3648906 | 0.98 | ANXA2 (0.33) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL3654646 | 0.80 | ABCC9 (0.34) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| Carbamic Acid SCHEMBL3651236 | 0.80 | CA2 (0.35) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| Hydrochloric Acid SCHEMBL3649320 | 0.76 | CA12 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4134961 | 0.75 | GAA (0.38) | ANXA2S100A10THRBALDH1A1GAA | |
| SCHEMBL3650248 | 0.73 | L3MBTL1 (0.34) | MEN1KMT2AANXA2S100A10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3649181 | 0.73 | LIPG (0.31) | MEN1KMT2AMMP9MMP13CYP2C9 | |
| Carbamic Acid SCHEMBL3648907 | 0.72 | HTT (0.34) | MEN1KMT2AANXA2S100A10SMN1; SMN2 | |
| SCHEMBL3650241 | 0.72 | HTR2C (0.38) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL3653515 | 0.70 | CA12 (0.35) | KMT2AABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |