Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349594 | 0.84 | HIF1A (0.41) | GAASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL4163587 | 0.80 | KDM4E (0.47) | GAASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL9173223 | 0.77 | ELANE (0.41) | JUNNFKB1GAARXRANR1H4 | |
| SCHEMBL15239733 | 0.75 | SMN1; SMN2 (0.50) | RXRANR1H4SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL15239737 | 0.75 | SMN1; SMN2 (0.50) | RXRANR1H4SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8042468 | 0.74 | MIF (0.53) | NFKB1GAASMN1; SMN2HTTKDM4E | |
| SCHEMBL7109844 | 0.72 | KDM4E (0.53) | JUNNFKB1GAARXRANR1H4 | |
| SCHEMBL7109843 | 0.72 | KDM4E (0.53) | JUNNFKB1GAARXRANR1H4 | |
| SCHEMBL10622820 | 0.70 | KDM4E (0.36) | GAARXRASMN1; SMN2HTTKDM4E | |
| SCHEMBL15239754 | 0.69 | HIF1A (0.55) | SMN1; SMN2KDM4EHIF1ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180264165-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2018-09-20 | — | — | US | claimed |
| US-9993576-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2018-06-12 | — | — | US | claimed |
| EP-2192886-B1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | PIONEER SURGICAL TECH INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-20170333594-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2017-11-23 | — | — | US | claimed |
| US-9757493-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2017-09-12 | — | — | US | claimed |
| US-20160250376-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | TUTOGEN MEDICAL, INC. | 2016-09-01 | — | — | US | claimed |
| US-20090270527-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | ANGSTROM MEDICA (US) | 2009-10-29 | — | — | US | claimed |
| US-10799610-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10413632-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180264165-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2018-09-20 | — | — | US | disclosed |
| US-9993576-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2192886-B1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | PIONEER SURGICAL TECH INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-20170333594-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2017-11-23 | — | — | US | disclosed |
| US-20160250376-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | TUTOGEN MEDICAL, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9358319-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140357754-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2014-12-04 | — | — | US | disclosed |
| US-8815973-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2192886-A2 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | Pioneer Surgical Technology, Inc. (US) | 2010-06-09 | — | — | EP | disclosed |
| US-20090270527-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | ANGSTROM MEDICA (US) | 2009-10-29 | — | — | US | disclosed |
| WO-2009029734-A2 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180264165-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | JUN 4061/4885NFKB1 2395/4885GAA 3591/4885 |
| US-20160250376-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | JUN 4061/4885NFKB1 2395/4885GAA 3591/4885 |
| US-20170333594-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | JUN 4061/4885NFKB1 2395/4885GAA 3591/4885 |
| US-10799610-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | JUN 4061/4885NFKB1 2395/4885GAA 3591/4885 |
| US-10413632-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | JUN 4061/4885NFKB1 2395/4885GAA 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.