Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1103989 | 0.87 | GPR119 (0.51) | FAAHALDH1A1 | |
| SCHEMBL25470925 | 0.76 | CYP2C19 (0.61) | FAAHGAANPC1RAB9AALDH1A1 | |
| SCHEMBL1103992 | 0.76 | HTT (0.57) | GAANPC1RAB9AALDH1A1HTT | |
| SCHEMBL7225805 | 0.74 | NPY5R (0.49) | MMP3NPY5RUSP5KMT2A | |
| SCHEMBL25316484 | 0.74 | HTT (0.43) | MMP3ALDH1A1NPY5RHTTRECQL | |
| SCHEMBL1092345 | 0.74 | GPR119 (0.57) | — | |
| SCHEMBL23064573 | 0.74 | ALDH1A1 (0.71) | FAAHGAANPC1RAB9AALDH1A1 | |
| SCHEMBL1103987 | 0.74 | FAAH (0.56) | FAAHGAAALDH1A1HTTRECQL | |
| SCHEMBL12745808 | 0.73 | GAA (0.69) | FAAHGAANPC1RAB9AALDH1A1 | |
| SCHEMBL28785031 | 0.73 | ALDH1A1 (0.74) | FAAHGAANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197873-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009038974-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-03-26 | — | — | WO | disclosed |