Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957021 | 0.80 | FAAH (0.61) | FAAHHTTSMN1; SMN2LMNASLC18A3 | |
| SCHEMBL6095340 | 0.76 | SMN1; SMN2 (0.54) | MAPTHTTRECQLSMN1; SMN2LMNA | |
| SCHEMBL1103992 | 0.74 | HTT (0.57) | MAPTHTTSMN1; SMN2KMT2ACYP2D6 | |
| SCHEMBL3650778 | 0.74 | FAAH (0.50) | FAAHHTTRECQLSMN1; SMN2KMT2A | |
| SCHEMBL27935616 | 0.73 | SIGMAR1 (0.67) | MAPTHTTRECQLSMN1; SMN2LMNA | |
| SCHEMBL26374 | 0.73 | GAA (0.65) | MAPTSMN1; SMN2KMT2AGAAMGLL | |
| SCHEMBL25316484 | 0.73 | HTT (0.43) | HTTRECQLSMN1; SMN2KMT2ACYP2D6 | |
| SCHEMBL7529885 | 0.72 | SMN1; SMN2 (0.52) | FAAHMAPTHTTRECQLSMN1; SMN2 | |
| SCHEMBL4184580 | 0.72 | ALDH1A1 (0.58) | FAAHMAPTHTTLMNASLC18A3 | |
| Hydrochloric Acid SCHEMBL7895043 | 0.72 | GAA (0.62) | MAPTSMN1; SMN2KMT2AGAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153635-B2 | Compounds and compositions as modulators of GPR119 activity | IRM LLC (BM) | 2012-04-10 | — | — | US | disclosed |
| US-20090270409-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270409-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | FAAH 744/4885MAPT 3590/4885HTT 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.