Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319664 | 0.80 | ADORA1 (0.52) | ACP1 | |
| SCHEMBL8324351 | 0.78 | MAPT (0.46) | KDM4EALDH1A1CXCR3MEN1KMT2A | |
| SCHEMBL8328108 | 0.73 | MAPT (0.40) | KDM4ERAB9A | |
| SCHEMBL10900630 | 0.69 | MEN1 (0.63) | RAB9AMEN1KMT2AAHRNPBWR1 | |
| SCHEMBL3650858 | 0.69 | GABRA1 (0.52) | ACP1CXCR3TP53NPBWR1 | |
| SCHEMBL8324694 | 0.69 | MAPT (0.40) | KDM4ERAB9A | |
| Water SCHEMBL8459983 | 0.67 | NR3C1 (0.34) | AHRTP53BACE1NPBWR1RECQL | |
| SCHEMBL8322607 | 0.67 | MEN1 (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8466131 | 0.66 | MAPT (0.42) | KDM4ERAB9A | |
| SCHEMBL4112905 | 0.66 | PPARA (0.46) | MEN1KMT2ANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888347-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034893-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-09-25 | — | — | WO | disclosed |