Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | RXRB | P28702 | 1/20 | 0.64 |
| ▸ | RXRG | P48443 | 1/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL16239962 | 0.94 | RXRA (0.58) | RXRARXRBRXRGSCN9ABCL2L1 | |
| SCHEMBL365474 | 0.88 | MAOB (0.67) | RXRARXRBRXRGBCL2L1MCL1 | |
| SCHEMBL364835 | 0.86 | SMPD1 (0.60) | SCN9ABCL2L1MCL1SMPD1MAOB | |
| SCHEMBL20773035 | 0.85 | SMPD1 (0.58) | SCN9ABCL2L1MCL1SMPD1MAOA | |
| SCHEMBL366081 | 0.85 | MAOA (0.63) | SCN9ABCL2L1MCL1MAOAMAOB | |
| SCHEMBL365210 | 0.85 | MAOA (0.63) | SCN9ABCL2L1MCL1MAOAMAOB | |
| SCHEMBL16240196 | 0.84 | SCN9A (0.77) | SCN9ABCL2L1MCL1SLC6A5MRGPRX4 | |
| SCHEMBL365207 | 0.83 | SCN9A (0.51) | RXRARXRBRXRGSCN9ABCL2L1 | |
| SCHEMBL678903 | 0.82 | BCL2L1 (0.52) | SCN9ABCL2L1MCL1NPC1RAB9A | |
| Diethylamine SCHEMBL14890330 | 0.81 | SMPD1 (0.55) | SCN9ABCL2L1MCL1SMPD1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096500-B2 | Acyl sulfonamide compounds | PFIZER LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| EP-2593428-A2 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| US-20130109701-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| WO-2012007868-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109701-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | RXRA 1658/4885RXRB 1975/4885RXRG 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.