Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366081 | 1.00 | MAOA (0.63) | MAOAMAOBBCL2L1MCL1NR4A2 | |
| Diethylamine SCHEMBL16239880 | 0.94 | MAOA (0.56) | MAOAMAOBBCL2L1MCL1NR4A2 | |
| SCHEMBL367348 | 0.88 | BCL2L1 (0.57) | MAOAMAOBBCL2L1MCL1NR4A2 | |
| SCHEMBL365645 | 0.88 | ALDH1A1 (0.70) | BCL2L1MCL1NPC1RAB9ASCN9A | |
| SCHEMBL16239768 | 0.88 | ALDH1A1 (0.70) | BCL2L1MCL1NPC1RAB9ASCN9A | |
| SCHEMBL364340 | 0.88 | RXRA (0.62) | BCL2L1MCL1NR4A2NPC1RAB9A | |
| SCHEMBL366812 | 0.86 | MAOB (0.63) | MAOBBCL2L1MCL1NR4A2SCN9A | |
| SCHEMBL365173 | 0.86 | MAOB (0.61) | MAOBBCL2L1MCL1NR4A2NPC1 | |
| SCHEMBL10203178 | 0.86 | SCN9A (0.66) | MAOAMAOBBCL2L1MCL1SCN9A | |
| SCHEMBL16240196 | 0.86 | SCN9A (0.77) | BCL2L1MCL1SCN9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096500-B2 | Acyl sulfonamide compounds | PFIZER LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| EP-2593428-A2 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| US-20130109701-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| WO-2012007868-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109701-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | MAOA 3705/4885MAOB 3660/4885BCL2L1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.