Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 8/20 | 0.61 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28611338 | 1.00 | CHKA (0.61) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL93665 | 0.97 | CHKA (0.59) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL636283 | 0.95 | LMNA (0.63) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30164362 | 0.95 | CHKA (0.57) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28628612 | 0.95 | CHKA (0.57) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11598831 | 0.92 | LMNA (0.61) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28191834 | 0.92 | CHKA (0.55) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Fluoride SCHEMBL22472142 | 0.92 | CHKA (0.55) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Bromide SCHEMBL2831425 | 0.92 | ACHE (0.68) | CHKALMNAALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31549504 | 0.90 | LMNA (0.59) | CHKALMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847867-B | Composite membranes having improved performance and/or durability and methods of use thereof | 3M创新有限公司 | 2021-06-25 | — | — | CN | claimed |
| US-20200164319-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2020-05-28 | — | — | US | claimed |
| US-20200030748-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2020-01-30 | — | — | US | claimed |
| US-10478778-B2 | Composite membranes with improved performance and/or durability and methods of use | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-11-19 | — | — | US | claimed |
| US-20180154311-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2018-06-07 | — | — | US | claimed |
| EP-3316998-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M Innovative Properties Company (US) | 2018-05-09 | — | — | EP | claimed |
| WO-2017004495-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-01-05 | — | — | WO | claimed |
| US-20120136189-A1 | BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION | CONOCOPHILLIPS COMPANY - IP SERVICES GROUP (US) | 2012-05-31 | — | — | US | claimed |
| WO-2011112514-A1 | BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION | CONOCOPHILLIPS COMPANY (US) | 2011-09-15 | — | — | WO | claimed |
| US-20110185788-A1 | IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY | KOCH PETER | 2011-08-04 | — | — | US | claimed |
| US-20020189444-A1 | Purification of gas with liquid ionic compounds | NATIONAL SCIENCE FOUNDATION | 2002-12-19 | — | — | US | claimed |
| EP-1015433-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE-10-OLES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-07-05 | — | — | EP | claimed |
| US-5994602-A | IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE | BP CHEMICALS LIMITED (GB) | 1999-11-30 | — | — | US | claimed |
| WO-1999014199-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE-10-OLES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-03-25 | — | — | WO | claimed |
| WO-1998047616-A1 | CATALYST COMPRISING A BUFFERED IONIC LIQUID AND HYDROCARBON CONVERSION PROCESS, E.G. OLIGOMERISATION | BP CHEMICALS LIMITED (GB) | 1998-10-29 | — | — | WO | claimed |
| EP-0693045-B1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1997-10-22 | — | — | EP | claimed |
| EP-0791643-A1 | Lubricating oils | BP Chemicals Limited (GB) | 1997-08-27 | — | — | EP | claimed |
| EP-0693045-A1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1996-01-24 | — | — | EP | claimed |
| WO-1995021872-A1 | IONIC LIQUIDS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021806-A1 | ALKYLATION PROCESS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136189-A1 | BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION | OSBPL8, OSBP, OSBP2 | CHKA 4077/4885ACHE 4012/4885LMNA 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.