Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5154357 | 0.98 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL28243088 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL11620447 | 0.81 | CYP2D6 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL15302870 | 0.80 | CYP2D6 (0.68) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL11622509 | 0.80 | SLC6A2 (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| Hydrochloric Acid SCHEMBL11686957 | 0.79 | LMNA (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| Hydrochloric Acid SCHEMBL11685187 | 0.79 | LMNA (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL30080140 | 0.78 | ABCB11 (0.66) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| SCHEMBL28000601 | 0.78 | ABCB11 (0.66) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 | |
| Hydrochloric Acid SCHEMBL28000604 | 0.78 | LMNA (0.68) | ALDH1A1LMNAMAPTSMN1; SMN2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115980202-B | High performance liquid chromatography detection method for bromhexine hydrochloride crude drug related substances | 山东齐都药业有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-115980202-A | High performance liquid chromatography detection method for related substances of bromhexine hydrochloride bulk drug | 山东齐都药业有限公司 | 2023-04-18 | — | — | CN | claimed |
| WO-2022233109-A1 | RUBBER CONTAINING MODIFIED GRAPHENE | 福建师范大学泉港石化研究院 | 2022-11-10 | — | — | WO | claimed |
| CN-113185759-B | Rubber containing modified graphene | 福建师范大学泉港石化研究院 | 2022-04-01 | — | — | CN | claimed |
| CN-113185759-A | Rubber containing modified graphene | 福建师范大学泉港石化研究院 | 2021-07-30 | — | — | CN | claimed |
| CN-104356002-A | Preparation process of impurities contained in expectorant drug bromhexine hydrochloride | UNIV HEBEI MEDICAL | 2015-02-18 | — | — | CN | claimed |
| WO-1997006131-A1 | METHOD OF PREPARING BENZYLAMINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1997-02-20 | — | — | WO | claimed |
| CN-115980202-B | High performance liquid chromatography detection method for bromhexine hydrochloride crude drug related substances | 山东齐都药业有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-115980202-A | High performance liquid chromatography detection method for related substances of bromhexine hydrochloride bulk drug | 山东齐都药业有限公司 | 2023-04-18 | — | — | CN | disclosed |
| WO-2023058050-A1 | A PROCESS FOR PREPARATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS VIA SELECTIVE NITRO REDUCTION REACTIONS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-04-13 | — | — | WO | disclosed |
| WO-2022233109-A1 | RUBBER CONTAINING MODIFIED GRAPHENE | 福建师范大学泉港石化研究院 | 2022-11-10 | — | — | WO | disclosed |
| CN-113185759-B | Rubber containing modified graphene | 福建师范大学泉港石化研究院 | 2022-04-01 | — | — | CN | disclosed |
| CN-113185759-B | Rubber containing modified graphene | 福建师范大学泉港石化研究院 | 2022-04-01 | — | — | CN | disclosed |
| US-20090246820-A1 | COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH | VERTEX PHARMACEUTICALS INCORPORATED | 2009-10-01 | — | — | US | disclosed |
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-09-10 | — | — | US | disclosed |
| US-7495103-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
| US-20050209334-A1 | method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. | NEW YORK UNIVERSITY (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885LMNA 2816/4885MAPT 4269/4885 |
| US-20050209334-A1 | method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. | AHR, TYR, CYP4X1 | ALDH1A1 598/4885LMNA 3667/4885MAPT 3055/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | ALDH1A1 2651/4885LMNA 3399/4885MAPT 4775/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | ALDH1A1 2221/4885LMNA 3499/4885MAPT 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.