SCHEMBL3653142

SCHEMBL3653142

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nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.40
CA12 O43570 7/20 0.40
CA9 Q16790 6/20 0.40
CA1 P00915 6/20 0.40
LGALS3 P17931 3/20 0.39
FGF1 P05230 1/20 0.38
MAPK1 P28482 1/20 0.37
LGALS1 P09382 2/20 0.36
LGALS9 O00182 1/20 0.36
LGALS8 O00214 1/20 0.36
MAPT P10636 1/20 0.36
PYGB P11216 1/20 0.36
SLC2A1 P11166 1/20 0.35
CA4 P22748 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA5B Q9Y2D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3948805 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL22121795 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL8003273 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL7049511 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL1116554 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL29993884 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL1116557 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
SCHEMBL1116556 1.00 CA2 (0.40) CA2CA12CA9CA1LGALS3
Sulfuric Acid SCHEMBL14764221 0.98 CA2 (0.39) CA2CA12CA9CA1LGALS3
SCHEMBL8201748 0.89 LGALS3 (0.39) CA2CA12CA9CA1LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2205616-A1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES Progen Pharmaceuticals Limited (AU) 2010-07-14 EP claimed
WO-2009049370-A1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2009-04-23 WO claimed
EP-2668198-A1 FGF RECEPTOR-ACTIVATING 3-O-ALKYL OLIGOSACCHARIDES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-12-04 EP disclosed
WO-2012101605-A1 FGF RECEPTOR-ACTIVATING 3-O-ALKYL OLIGOSACCHARIDES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-08-02 WO disclosed
US-20110150984-A1 METHODS OF INCREASING THE BIOAVAILABILITY AND/OR CELLULAR UPDATE OF DRUGS HET NEDERLANDS KANKER INSTITUUT (NL) 2011-06-23 US disclosed
US-7915227-B2 Pharmaceutical formulations employing short-chain sphingolipids and their use HET NEDERLANDS KANKER INSTITUUT (NL) 2011-03-29 US disclosed
US-20070082855-A1 Pharmaceutical formulations employing short-chain sphingolipids and their use HET NEDERLANDS KANKER INSTITUUT (NL) 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150984-A1 METHODS OF INCREASING THE BIOAVAILABILITY AND/OR CELLULAR UPDATE OF DRUGS NPC1L1, SGMS2, SGMS1 CA2 2144/4885CA12 1872/4885CA9 2923/4885
US-20070082855-A1 Pharmaceutical formulations employing short-chain sphingolipids and their use SGMS1, SGMS2, CERT1 CA2 2346/4885CA12 1285/4885CA9 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.