Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364784 | 0.86 | KDM4E (0.47) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL366971 | 0.86 | MAPT (0.48) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL365354 | 0.85 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL366340 | 0.84 | MAOB (0.49) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL364674 | 0.84 | KDM4E (0.48) | ALDH1A1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL4477445 | 0.83 | RXRA (0.50) | ALDH1A1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL364702 | 0.82 | KDM4E (0.45) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL367034 | 0.82 | ELANE (0.48) | ALDH1A1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL364182 | 0.81 | MAOB (0.46) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL364482 | 0.80 | KDM4E (0.48) | ALDH1A1KMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |