Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650309 | 0.94 | KMT2A (0.50) | KMT2ARAB9AMEN1NPC1EPHX2 | |
| Trifluoroacetic Acid SCHEMBL3650317 | 0.87 | EPHX2 (0.43) | KMT2ARAB9AMEN1NPC1EPHX2 | |
| Trifluoroacetic Acid SCHEMBL3650438 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL3705581 | 0.84 | KDM4E (0.40) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3660920 | 0.84 | HRH3 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL3657860 | 0.83 | RAB9A (0.39) | KMT2ARAB9AMEN1NPC1HPGD | |
| Trifluoroacetic Acid SCHEMBL3656237 | 0.82 | MLYCD (0.41) | KMT2ARAB9AMEN1NPC1 | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.82 | NPC1 (0.39) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3656228 | 0.82 | RAB9A (0.46) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3657956 | 0.81 | HRH3 (0.44) | KMT2ARAB9AMEN1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212283-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052062-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |