Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.40 |
| ▸ | BCL9 | O00512 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652477 | 0.94 | ESR1 (0.45) | ESR1CTNNB1BCL9P2RY14LRRK2 | |
| Trifluoroacetic Acid SCHEMBL3650438 | 0.90 | — | — | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.86 | NPC1 (0.39) | CTNNB1BCL9MEN1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3705581 | 0.85 | KDM4E (0.40) | CTNNB1BCL9MEN1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3657556 | 0.85 | HSP90AA1 (0.45) | MEN1NPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL3655792 | 0.85 | MAPT (0.37) | MLYCDESR1CTNNB1BCL9P2RY14 | |
| Trifluoroacetic Acid SCHEMBL3656228 | 0.85 | RAB9A (0.46) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3655153 | 0.83 | NPC1 (0.43) | MEN1NPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL3657860 | 0.83 | RAB9A (0.39) | MEN1NPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL3655094 | 0.83 | CYP2C9 (0.49) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |