Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3652805 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1RAB9AKMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3657860 | 0.88 | RAB9A (0.39) | RAB9AKMT2ANPC1MAPTMEN1 | |
| Trifluoroacetic Acid SCHEMBL3650438 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL3656237 | 0.85 | MLYCD (0.41) | RAB9AKMT2ANPC1BCL9CTNNB1 | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.84 | NPC1 (0.39) | KDM4ERAB9AKMT2ANPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL3653647 | 0.84 | KMT2A (0.45) | ALDH1A1RAB9AKMT2ANPC1MEN1 | |
| Trifluoroacetic Acid SCHEMBL3660920 | 0.84 | HRH3 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL3656228 | 0.83 | RAB9A (0.46) | ALDH1A1RAB9AKMT2ANPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL3657556 | 0.82 | HSP90AA1 (0.45) | KDM4EALDH1A1RAB9AKMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3650183 | 0.81 | MAPK14 (0.33) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |