Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551983 | 0.93 | TSHR (0.60) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL931931 | 0.87 | TSHR (0.54) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL18896444 | 0.82 | TSHR (0.59) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL20721895 | 0.82 | TSHR (0.59) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL11670749 | 0.81 | TSHR (0.61) | TSHRCYP1A2ALOX15KIF11 | |
| Benzoic Acid SCHEMBL28194477 | 0.80 | TSHR (0.64) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL407595 | 0.80 | TSHR (0.56) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL5311010 | 0.80 | TSHR (0.56) | TSHRDAONAPRTTP53SRD5A2 | |
| SCHEMBL3370870 | 0.79 | TSHR (0.60) | TSHRDAONAPRTTP53SRD5A2 | |
| Benzoic Acid SCHEMBL11359136 | 0.79 | TSHR (0.78) | TSHRDAONAPRTTP53SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290586-B2 | Solid catalyst component, catalyst comprising said solid component, and process for the (CO)polymerization of α-olefins | VERSALIS S.P.A. (IT) | 2016-03-22 | — | — | US | disclosed |
| US-20160060370-A1 | SOLID CATALYST COMPONENT, CATALYST COMPRISING SAID SOLID COMPONENT, AND PROCESS FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS | VERSALIS S.P.A. (IT) | 2016-03-03 | — | — | US | disclosed |
| US-20130303360-A1 | SOLID CATALYST COMPONENT, CATALYST COMPRISING SAID SOLID COMPONENT, AND PROCESS FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS | VERSALIS S.P.A. (IT) | 2013-11-14 | — | — | US | disclosed |
| EP-2593427-A1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007883-A1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |