SCHEMBL3370870

SCHEMBL3370870

O=C(O)c1ccc(C(Cl)(Cl)Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
TP53 P04637 1/20 0.60
ALOX15 P16050 1/20 0.54
SRD5A2 P31213 5/20 0.54
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
RARB P10826 1/20 0.48
RARG P13631 1/20 0.48
TPMT P51580 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL11451992 0.98 SRD5A2 (0.57) TSHRTP53ALOX15SRD5A2CA1
Hydrochloric Acid SCHEMBL11249823 0.98 TSHR (0.57) TSHRTP53ALOX15SRD5A2CA1
Methane SCHEMBL11452166 0.98 TSHR (0.57) TSHRTP53ALOX15SRD5A2CA1
Benzoic Acid SCHEMBL28194477 0.86 TSHR (0.64) TSHRTP53ALOX15SRD5A2ALDH1A1
SCHEMBL3551983 0.85 TSHR (0.60) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL3701394 0.82 SRD5A2 (0.50) TSHRSRD5A2ALDH1A1CES2CES1
Terephthalic Acid SCHEMBL1243625 0.81 TSHR (0.80) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL104711 0.80 ALDH1A1 (0.45) TSHRTP53SRD5A2ALDH1A1SMN1; SMN2
SCHEMBL931931 0.79 TSHR (0.54) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL2980698 0.79 ALDH1A1 (0.61) TSHRSRD5A2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102968-A Preparation method of modified polyurethane waterproof coating 泰州市高士建筑材料科技有限公司 2023-05-12 CN claimed
CN-121272436-A Catalytic system and method for electrochemical reduction and oxygenation of 1, 4-bis (trichloromethyl) benzene to 4- (trichloromethyl) benzoic acid 浙江工业大学 2026-01-06 CN disclosed
CN-121272436-A Catalytic system and method for electrochemical reduction and oxygenation of 1, 4-bis (trichloromethyl) benzene to 4- (trichloromethyl) benzoic acid 浙江工业大学 2026-01-06 CN disclosed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
CN-116102968-A Preparation method of modified polyurethane waterproof coating 泰州市高士建筑材料科技有限公司 2023-05-12 CN disclosed
CN-116102968-A Preparation method of modified polyurethane waterproof coating 泰州市高士建筑材料科技有限公司 2023-05-12 CN disclosed
CN-115398342-A Film-forming composition 日产化学株式会社 2022-11-25 CN disclosed
US-8669375-B2 Process for producing ester compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-11 US disclosed
US-20130066070-A1 PROCESS FOR PRODUCING ESTER COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-03-14 US disclosed
US-8318964-B2 Process for producing ester compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-11-27 US disclosed
US-5296496-A Treating degenerative diseases STERLING WINTHROP INC. (US) 1994-03-22 US disclosed
US-5250696-A Treatment of degenerative diseases STERLING WINTHROP INC. (US) 1993-10-05 US disclosed
EP-0550111-A1 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them STERLING WINTHROP INC. (US) 1993-07-07 EP disclosed
EP-0550112-A1 2-Saccharinylmethyl aryl and aryloxy acetates useful as proteolytic enzyme inhibitors and pharmaceutical compositions contaning them STERLING WINTHROP INC. (US) 1993-07-07 EP disclosed
EP-0549073-A1 Novel 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof STERLING WINTHROP INC. (US) 1993-06-30 EP disclosed
US-5187173-A Degenerative diseases such as emphysema, rheumatoid arthritis, pancreatitis, cyctic fibrosis and skin disorders STERLING WINTHROP INC. (US) 1993-02-16 US disclosed
US-5128339-A Emphysema, rheumatoid arthritis, pancreatitis STERLING WINTHROP INC. (US) 1992-07-07 US disclosed
EP-0483928-A1 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use STERLING WINTHROP INC. (US) 1992-05-06 EP disclosed
EP-0440995-A1 Process for preparing 1-octene SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-14 EP disclosed
US-5030792-A Process for preparing 1-octene SHELL OIL COMPANY (US) 1991-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066070-A1 PROCESS FOR PRODUCING ESTER COMPOUND ADH1C, ADH5, ADH1A TSHR 2444/4885TP53 1748/4885ALOX15 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.