Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLR1A | O95602 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366299 | 0.89 | LMNA (0.38) | POLR1APARP1LMNAPRNPCYP1A2 | |
| SCHEMBL366185 | 0.85 | CYP1A2 (0.42) | LMNAPRNPCYP1A2CHRM2HTR1A | |
| SCHEMBL364304 | 0.84 | CHRM1 (0.38) | LMNAPRNPCYP1A2CHRM2HTR1A | |
| SCHEMBL366837 | 0.82 | ALDH1A1 (0.40) | LMNAPRNPCYP1A2CHRM2HTR1A | |
| SCHEMBL366238 | 0.82 | CYP1A2 (0.44) | POLR1ALMNAPRNPCYP1A2CHRM2 | |
| SCHEMBL364861 | 0.82 | EGFR (0.51) | POLR1ALMNACYP1A2CYP2D6KCNH2 | |
| SCHEMBL364891 | 0.82 | MAPT (0.44) | POLR1APARP1LMNACYP1A2ALDH1A1 | |
| SCHEMBL365488 | 0.81 | PARP1 (0.41) | POLR1APARP1TACR1ALDH1A1HPGD | |
| SCHEMBL367568 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL365761 | 0.81 | ALDH1A1 (0.43) | POLR1ALMNAPRNPCYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |