Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.79 |
| ▸ | PGR | P06401 | 7/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.79 |
| ▸ | AR | P10275 | 4/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flurandrenolide SCHEMBL3692151 | 0.88 | CYP3A4 (0.97) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL13423594 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL5490827 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL21111542 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL5042122 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL4694 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| Flurandrenolide SCHEMBL13769220 | 0.88 | CYP3A4 (1.00) | CYP3A4NR3C1PGRHIF1AAR | |
| SCHEMBL42575 | 0.84 | NR3C1 (0.78) | CYP3A4NR3C1PGRHIF1AAR | |
| SCHEMBL10028415 | 0.80 | PGR (0.85) | CYP3A4NR3C1PGRHIF1AAR | |
| SCHEMBL11862078 | 0.79 | CYP3A4 (0.80) | CYP3A4NR3C1PGRHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096498-A1 | INJECTABLE SUSTAINED-RELEASE FORMULATIONS FOR TREATMENT OF JOINT PAIN AND INFLAMMATION | FORDOZ PHARMA CORP. (US) | 2022-03-31 | — | — | US | claimed |
| WO-2020227353-A1 | INJECTABLE SUSTAINED-RELEASE FORMULATIONS FOR TREATMENT OF JOINT PAIN AND INFLAMMATION | FORDOZ PHARMA CORP. (US) | 2020-11-12 | — | — | WO | claimed |
| CN-101443030-A | Use of gelsolin for diagnosis and treatment of inflammatory diseases | BRIGHAM & WOMENS HOSPITAL (US) | 2009-05-27 | — | — | CN | claimed |
| US-20220096498-A1 | INJECTABLE SUSTAINED-RELEASE FORMULATIONS FOR TREATMENT OF JOINT PAIN AND INFLAMMATION | FORDOZ PHARMA CORP. (US) | 2022-03-31 | — | — | US | disclosed |
| WO-2020227353-A1 | INJECTABLE SUSTAINED-RELEASE FORMULATIONS FOR TREATMENT OF JOINT PAIN AND INFLAMMATION | FORDOZ PHARMA CORP. (US) | 2020-11-12 | — | — | WO | disclosed |
| EP-2201036-A1 | TRANSFERRIN VARIANTS AND CONJUGATES | Novozymes Biopharma DK A/S (DK) | 2010-06-30 | — | — | EP | disclosed |
| CN-101443030-A | Use of gelsolin for diagnosis and treatment of inflammatory diseases | BRIGHAM & WOMENS HOSPITAL (US) | 2009-05-27 | — | — | CN | disclosed |
| WO-2009019314-A1 | TRANSFERRIN VARIANTS AND CONJUGATES | NOVOZYMES A/S (DK) | 2009-02-12 | — | — | WO | disclosed |
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |