Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662128 | 0.91 | TSHR (0.35) | TSHRHTTL3MBTL1RIPK1EPHX2 | |
| SCHEMBL3655106 | 0.86 | F2 (0.38) | RIPK1EPHX2MALT1DDR1TP53 | |
| SCHEMBL977615 | 0.86 | ALOX5 (0.39) | L3MBTL1EPHX2LMNAMALT1CACNA1G | |
| SCHEMBL977174 | 0.85 | SCN9A (0.35) | SCN9ASCN7ASCN5ALMNATP53 | |
| SCHEMBL976850 | 0.84 | SCN9A (0.34) | SCN9ASCN7ASCN5ALMNADDR1 | |
| SCHEMBL3656172 | 0.83 | F2 (0.46) | EPHX2LMNAMALT1TP53SLC6A9 | |
| SCHEMBL977991 | 0.83 | TRPA1 (0.37) | SCN9ASCN7ASCN5ALMNATP53 | |
| SCHEMBL977176 | 0.83 | SLC6A9 (0.38) | SCN9ASCN7ASCN5ALMNASLC6A9 | |
| SCHEMBL3659731 | 0.83 | F2 (0.38) | MALT1DDR1 | |
| SCHEMBL978426 | 0.82 | ALDH1A1 (0.39) | TSHRSCN9ASCN7ASCN5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234966-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Sanofi-Aventis (FR) | 2010-10-06 | — | — | EP | claimed |
| WO-2009106708-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | claimed |