Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 8/20 | 0.55 |
| ▸ | UQCRB | P14927 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747439 | 0.80 | ACLY (0.60) | HSD17B2UQCRBCA1CA2ALDH1A1 | |
| SCHEMBL2747919 | 0.78 | LMNA (0.74) | HSD17B2UQCRBALDH1A1MEN1MAPT | |
| SCHEMBL7587850 | 0.77 | HSD17B2 (0.79) | HSD17B2UQCRBCA1CA2ALDH1A1 | |
| SCHEMBL812679 | 0.73 | ALDH1A1 (0.83) | UQCRBCA1CA2ALDH1A1MEN1 | |
| SCHEMBL15248886 | 0.73 | HSD17B2 (0.74) | HSD17B2UQCRBCA1CA2ALDH1A1 | |
| SCHEMBL13476997 | 0.73 | SCN9A (0.36) | HSD17B2MEN1KMT2A | |
| SCHEMBL4550967 | 0.72 | MAPT (0.61) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL1040954 | 0.71 | ALDH1A1 (0.73) | HSD17B2UQCRBCA1CA2ALDH1A1 | |
| SCHEMBL13433558 | 0.71 | ALDH1A1 (0.73) | HSD17B2UQCRBCA1CA2ALDH1A1 | |
| SCHEMBL13852837 | 0.71 | HSD17B2 (0.68) | HSD17B2UQCRBCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220065-A2 | MODULATORS OF CCR9 RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009017719-A2 | MODULATORS OF CCR9 RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |