Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3657613 | 0.87 | SMN1; SMN2 (0.47) | CYP2C9HIF1AEPAS1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3650438 | 0.86 | — | — | |
| Trifluoroacetic Acid SCHEMBL3656237 | 0.83 | MLYCD (0.41) | RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.80 | NPC1 (0.39) | RAB9ANPC1TP53POLBSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3705581 | 0.80 | KDM4E (0.40) | RAB9ANPC1ALDH1A1POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL3656228 | 0.80 | RAB9A (0.46) | RAB9ANPC1LMNATP53ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3653647 | 0.79 | KMT2A (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| Trifluoroacetic Acid SCHEMBL3657556 | 0.78 | HSP90AA1 (0.45) | RAB9ANPC1LMNATP53ALDH1A1 | |
| SCHEMBL3655153 | 0.78 | NPC1 (0.43) | RAB9ANPC1TP53ALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3657860 | 0.78 | RAB9A (0.39) | RAB9ANPC1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |