SCHEMBL3657653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13629967	0.82	ADORA3 (0.50)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL13622956	0.79	ADORA3 (0.47)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL13615797	0.78	ADORA3 (0.46)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL3647330	0.77	CDC25A (0.38)	PIK3CAPI4KAPI4KBPIK3CDPIK3CB
	SCHEMBL12681394	0.73	ADORA3 (0.54)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL4355883	0.73	LOXL2 (0.50)	PIK3CAPI4KAPI4KBPIK3CDPIK3CB
	SCHEMBL12680080	0.71	ADORA3 (0.51)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL15071926	0.70	ADORA3 (0.50)	ADORA3ADORA2AADORA2BADORA1PIK3CA
	SCHEMBL13906876	0.69	PIK3CA (0.39)	PIK3CAPI4KAPI4KBPIK3CDPIK3CB
	SCHEMBL13179479	0.68	CA12 (0.36)	PIK3CAPI4KAPI4KBPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.