Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365836 | 0.92 | MAPT (0.38) | ALOX5CNR2MAPTTP53THRB | |
| SCHEMBL365592 | 0.91 | MRGPRX4 (0.39) | MAPTTP53LTB4RLTB4R2LMNA | |
| SCHEMBL366850 | 0.91 | MAPT (0.37) | CNR2MAPTTP53THRBLTB4R | |
| SCHEMBL365985 | 0.86 | MEN1 (0.46) | ALOX5CNR2MAPTTP53THRB | |
| SCHEMBL365168 | 0.84 | ACHE (0.41) | LTB4RLTB4R2 | |
| SCHEMBL366373 | 0.83 | MAPT (0.37) | CNR2MAPTTP53THRBLTB4R | |
| SCHEMBL366480 | 0.83 | ACHE (0.39) | MAPTTP53LTB4RLTB4R2LMNA | |
| SCHEMBL365188 | 0.83 | CYP11B1 (0.39) | LTB4RLTB4R2LMNAPKMALDH1A1 | |
| SCHEMBL366750 | 0.83 | PPARG (0.33) | ALOX5CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL367733 | 0.82 | KMT2A (0.38) | MAPTLMNAPKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |