Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365592 | 0.92 | MRGPRX4 (0.39) | ACHEKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365924 | 0.92 | ACHE (0.42) | ACHEKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365836 | 0.91 | MAPT (0.38) | KDM4EMEN1APAF1ALDH1A1MAPT | |
| SCHEMBL366617 | 0.86 | MEN1 (0.45) | ACHEKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL366373 | 0.85 | MAPT (0.37) | ACHEKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365168 | 0.84 | ACHE (0.41) | ACHELTB4RLTB4R2CYP2D6 | |
| SCHEMBL365768 | 0.83 | ALOX5 (0.38) | KDM4EMEN1APAF1ALDH1A1MAPT | |
| SCHEMBL366611 | 0.83 | ACHE (0.38) | ACHEKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365489 | 0.81 | KMT2A (0.36) | MEN1ALDH1A1KMT2ARAB9APKM | |
| SCHEMBL366481 | 0.80 | ACHE (0.39) | ACHEPLK1LTB4RLTB4R2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |