Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365489 | 0.90 | KMT2A (0.36) | KMT2AALDH1A1PKMNCEH1RAB9A | |
| SCHEMBL365212 | 0.86 | KMT2A (0.39) | KMT2AALDH1A1PKMNCEH1RAB9A | |
| SCHEMBL365188 | 0.85 | CYP11B1 (0.39) | KMT2AALDH1A1PKMLMNA | |
| SCHEMBL366033 | 0.82 | NPC1 (0.40) | ALDH1A1ATMNPC1GAARXFP1 | |
| SCHEMBL365768 | 0.82 | ALOX5 (0.38) | KMT2AALDH1A1PKMRAB9ANPC1 | |
| SCHEMBL366019 | 0.81 | STS (0.41) | KMT2AALDH1A1ATMNPC1GAA | |
| SCHEMBL365592 | 0.80 | MRGPRX4 (0.39) | KMT2AALDH1A1PKMRAB9ANPC1 | |
| SCHEMBL366850 | 0.80 | MAPT (0.37) | KMT2AALDH1A1RXFP1MEN1KDM4E | |
| SCHEMBL366113 | 0.80 | EPHX1 (0.49) | KMT2ARAB9ANPC1GAAMEN1 | |
| SCHEMBL365175 | 0.80 | NPC1 (0.43) | ALDH1A1PKMATMNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |