Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367201 | 0.84 | EGFR (0.45) | EGFRSRC | |
| SCHEMBL366888 | 0.79 | EGFR (0.44) | EGFRSRCMEN1KMT2A | |
| SCHEMBL365854 | 0.75 | KDM4E (0.55) | LMNAEGFRSRCMEN1MAPT | |
| SCHEMBL364931 | 0.74 | NR4A2 (0.50) | LMNAEGFRSRCMEN1MAPT | |
| SCHEMBL30386248 | 0.73 | KDM4E (0.39) | LMNAMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL365622 | 0.71 | CA12 (0.46) | MEN1MAPTKMT2AADORA3F2 | |
| SCHEMBL364761 | 0.71 | KDM4E (0.52) | LMNAMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL365400 | 0.69 | ELANE (0.47) | LMNAMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL364542 | 0.69 | ALDH1A1 (0.59) | LMNAEGFRSRCMEN1MAPT | |
| SCHEMBL367764 | 0.68 | EGFR (0.45) | LMNAEGFRSRCMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |