SCHEMBL367201 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	3/20	0.45

▸	SRC	P12931	1/20	0.45

▸	HTR2A	P28223	1/20	0.40

▸	HTR2C	P28335	1/20	0.40

▸	KDM4E	B2RXH2	2/20	0.36

▸	RAB9A	P51151	1/20	0.35

▸	ELANE	P08246	1/20	0.35

▸	PLA2G2A	P14555	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.33

▸	NR4A2	P43354	1/20	0.33

▸	AGTR1	P30556	1/20	0.33

▸	CNR1	P21554	1/20	0.33

▸	PARP1	P09874	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL366888	0.85	EGFR (0.44)	EGFRSRCKDM4EALDH1A1AGTR1
SCHEMBL365855	0.84	LMNA (0.33)	EGFRSRC
SCHEMBL367764	0.84	EGFR (0.45)	EGFRSRCHTR2AHTR2CKDM4E
SCHEMBL365259	0.81	KDM4E (0.44)	EGFRSRCHTR2AHTR2CKDM4E
SCHEMBL364931	0.80	NR4A2 (0.50)	EGFRSRCKDM4EALDH1A1NR4A2
SCHEMBL367330	0.80	EGFR (0.46)	EGFRSRCHTR2AHTR2CKDM4E
SCHEMBL367705	0.79	EGFR (0.48)	EGFRSRCHTR2AHTR2CKDM4E
SCHEMBL364594	0.79	EGFR (0.44)	EGFRSRCKDM4EPLA2G2AALDH1A1
SCHEMBL367707	0.79	EGFR (0.44)	EGFRSRCHTR2AHTR2CAGTR1
SCHEMBL365635	0.77	IDO1 (0.44)	EGFRSRCHTR2AHTR2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012007008-A1	INHIBITORS OF HDME	EPITHERAPEUTICS APS (DK)	2012-01-19	—	—	WO	claimed
WO-2012007008-A1	INHIBITORS OF HDME	EPITHERAPEUTICS APS (DK)	2012-01-19	—	—	WO	disclosed