Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627129 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL4142499 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL10361210 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL5981668 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL29019053 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL3620222 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL4145466 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL4145587 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL24906216 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL388877 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | ALDH1A1 406/4885CA12 4172/4885CA1 3968/4885 |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | ALDH1A1 406/4885CA12 4172/4885CA1 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.