Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361210 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL3627129 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL4142499 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL3658992 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL4145466 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL10361212 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTTSHRMAPK1KDM4E | |
| SCHEMBL4158524 | 0.75 | LMNA (0.32) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10361848 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL29019053 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1KDM4ETDP1 | |
| SCHEMBL5981668 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-0154508-B1 | THIOPHENYLUREAS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4843100-A | Benzoylureas, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| US-4632938-A | INSECTICIDES, OVICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| EP-0154507-A2 | Benzoylureas, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-09-11 | — | — | EP | disclosed |
| EP-0154508-A2 | Thiophenylureas, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176786-A1 | Benzoylurea Compounds and Use Thereof | BTK, BRIX1, NFXL1 | ALDH1A1 1454/4885LMNA 2141/4885MAPT 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.