SCHEMBL365923

SCHEMBL365923

OCCc1cc(-c2cccs2)sc1-c1cccs1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.45
LTA4H P09960 1/20 0.39
KDM4E B2RXH2 4/20 0.37
NPC1 O15118 4/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GLA P06280 1/20 0.37
RAB9A P51151 3/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424299 0.95 DPP4 (0.49) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL22343408 0.88 DPP4 (0.50) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL14590760 0.81 SREBF2 (0.37) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL20146971 0.81 KDM4E (0.42) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL2608116 0.80 ADK (0.39) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL9198790 0.79 STK17B (0.35) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL352568 0.79 ALDH1A1 (0.47) DPP4KDM4ENPC1MAPTALDH1A1
SCHEMBL9976549 0.79 LTA4H (0.46) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL10070116 0.78 DPP4 (0.44) DPP4LTA4HKDM4ENPC1MAPT
SCHEMBL12018842 0.78 ADK (0.40) KDM4ENPC1MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10787579-B2 Sensors and separation based on molecular recognition via electropolymerization and colloidal layer templates UNIVERSITY OF HOUSTON SYSTEM (US) 2020-09-29 US claimed
US-10787579-B2 Sensors and separation based on molecular recognition via electropolymerization and colloidal layer templates UNIVERSITY OF HOUSTON SYSTEM (US) 2020-09-29 US disclosed
US-10787579-B2 Sensors and separation based on molecular recognition via electropolymerization and colloidal layer templates UNIVERSITY OF HOUSTON SYSTEM (US) 2020-09-29 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20120263922-A1 SENSORS AND SEPARATION BASED ON MOLECULAR RECOGNITION VIA ELECTROPOLYMERIZATION AND COLLOIDAL LAYER TEMPLATES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-10-18 US disclosed
US-20120263922-A1 SENSORS AND SEPARATION BASED ON MOLECULAR RECOGNITION VIA ELECTROPOLYMERIZATION AND COLLOIDAL LAYER TEMPLATES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-10-18 US disclosed
WO-2012009239-A2 SENSORS AND SEPARATION BASED ON MOLECULAR RECOGNITION VIA ELECTROPOLYMERIZATION AND COLLOIDAL LAYER TEMPLATES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 WO disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed
EP-2000803-A1 Nanoparticles with Polymer Shells Nanosphere, Inc. (US) 2008-12-10 EP disclosed
EP-1819719-A2 OLIGONUCLEOTIDE PROBES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2007-08-22 EP disclosed
EP-1135682-B1 NANOPARTICLES WITH POLYMER SHELLS NANOSPHERE INC (US) 2007-07-11 EP disclosed
US-7115688-B1 Nanoparticles with polymer shells NANOSPHERE, INC. (US) 2006-10-03 US disclosed
WO-2006051397-A2 OLIGONUCLEOTIDE PROBES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2006-05-18 WO disclosed