Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SDHB | P21912 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062482 | 0.92 | DPP4 (0.48) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10070116 | 0.83 | DPP4 (0.44) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL14590760 | 0.83 | SREBF2 (0.37) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19513782 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL22343408 | 0.82 | DPP4 (0.50) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9197880 | 0.81 | LTA4H (0.37) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2608116 | 0.81 | ADK (0.39) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL4798711 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL365923 | 0.81 | DPP4 (0.45) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL352568 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |