Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364980 | 0.90 | KDM4E (0.37) | CNR1CNR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL365938 | 0.89 | S1PR3 (0.34) | CNR1CNR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL364305 | 0.88 | ALDH1A1 (0.36) | CNR2ALDH1A1HPGDHDAC10HDAC6 | |
| SCHEMBL366838 | 0.84 | ALDH1A1 (0.41) | CNR2ALDH1A1HPGDHDAC10HDAC6 | |
| SCHEMBL366193 | 0.83 | ALDH1A1 (0.36) | CNR1ALDH1A1HPGDNAMPTKMT2A | |
| SCHEMBL366186 | 0.80 | ALDH1A1 (0.39) | CNR2ALDH1A1HPGDTSHRHDAC10 | |
| SCHEMBL367569 | 0.79 | SRC (0.46) | ALDH1A1HPGDSMN1; SMN2EGFRKMT2A | |
| SCHEMBL365762 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2AGAA | |
| SCHEMBL366442 | 0.78 | ALDH1A1 (0.42) | CNR1CNR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL366239 | 0.77 | PLA2G2A (0.41) | CNR2ALDH1A1HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |