Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364980 | 0.91 | KDM4E (0.37) | CNR2CNR1ALDH1A1KDM4ETP53 | |
| SCHEMBL366194 | 0.89 | CNR1 (0.35) | CNR2CNR1ALDH1A1KDM4ETP53 | |
| SCHEMBL365936 | 0.85 | S1PR3 (0.38) | S1PR3CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL365937 | 0.85 | S1PR3 (0.38) | S1PR3CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL364305 | 0.77 | ALDH1A1 (0.36) | CNR2ALDH1A1HPGDHDAC10HDAC6 | |
| SCHEMBL364979 | 0.76 | KDM4E (0.40) | CNR1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL364978 | 0.76 | KDM4E (0.40) | CNR1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL367061 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHDAC10HDAC6 | |
| SCHEMBL366193 | 0.75 | ALDH1A1 (0.36) | CNR1ALDH1A1KDM4ETP53GLA | |
| SCHEMBL366838 | 0.73 | ALDH1A1 (0.41) | CNR2ALDH1A1KDM4EHPGDHDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |