SCHEMBL365956

SCHEMBL365956

Cc1c(-c2ncc(-c3ccccc3)o2)ccc(-c2ncc(-c3ccccc3)o2)c1C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
CASP1 P29466 1/20 0.65
RAB9A P51151 7/20 0.63
NPC1 O15118 6/20 0.63
ATM Q13315 1/20 0.63
KMT2A Q03164 4/20 0.56
GAA P10253 4/20 0.56
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 5/20 0.56
HPGD P15428 5/20 0.56
HSD17B10 Q99714 4/20 0.56
MEN1 O00255 3/20 0.56
MITF O75030 1/20 0.56
CREBBP Q92793 2/20 0.54
PTPN1 P18031 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.49
TP53 P04637 3/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12794313 0.91 RAB9A (0.66) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL4342614 0.85 ALOX15 (0.69) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL1471533 0.85 RAB9A (0.77) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL4879849 0.84 RAB9A (0.66) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL3295181 0.81 RAB9A (0.72) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL74359 0.81 ALOX15 (0.96) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL10726923 0.79 ALOX15 (1.00) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL75219 0.79 ALOX15 (1.00) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL10495096 0.79 PTPN1 (0.73) ALOX15TSHRCASP1RAB9ANPC1
SCHEMBL5562081 0.79 ALOX15 (0.82) ALOX15TSHRCASP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638602-B2 Metal organic framework particles as radioisotope detectors ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-05-26 US claimed
US-12360107-B2 Synthesis of nanoSCINT particles ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERISTY OF ARIZONA (US) 2025-07-15 US claimed
WO-2025051780-A1 DYE-LOADED ZEOLITE COMPOSITE MATERIALS OPTICAL ADDITIVES GMBH (CH) 2025-03-13 WO claimed
EP-4516875-A1 DYE-LOADED ZEOLITE COMPOSITE MATERIALS Optical Additives GmbH (CH) 2025-03-05 EP claimed
US-20240280712-A1 METAL ORGANIC FRAMEWORK PARTICLES AS RADIOISOTOPE DETECTORS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2024-08-22 US claimed
EP-3714293-B1 SUBSTRATE INCLUDING SCINTILLATOR MATERIALS, SYSTEM INCLUDING SUBSTRATE, AND METHOD OF USE SAINT GOBAIN CERAMICS & PLASTICS INC (US) 2023-10-04 EP claimed
EP-4214557-A1 OPTICAL LIGHT GUIDE INCLUDING FLUORESCENT MATERIAL Luxium Solutions, LLC (US) 2023-07-26 EP claimed
WO-2023069767-A1 METAL ORGANIC FRAMEWORK PARTICLES AS β EMISSION DETECTORS IN AQUEOUS SYSTEMS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-04-27 WO claimed
US-20220381789-A1 NANOCOMPOSITE PARTICLES COMPRISING A BORONIC ACID MOIETY AND METHODS FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA, A BODY CORPORATE (US) 2022-12-01 US claimed
WO-2022231604-A1 NANOCOMPOSITE PARTICLES COMPRISING A BORONIC ACID MOIETY AND METHODS FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-11-03 WO claimed
US-6932919-B2 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2005-08-23 US claimed
US-20040026662-A1 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2004-02-12 US claimed
EP-1335879-A1 DYE LOADED ZEOLITE MATERIAL Universitaet Bern (CH) 2003-08-20 EP claimed
US-20030075720-A1 Organic light-emitting diode having an interface layer between the hole-transporting layer and the light-emitting layer EASTMAN KODAK COMPANY 2003-04-24 US claimed
WO-2002036490-A1 DYE LOADED ZEOLITE MATERIAL UNIVERSITAET BERN (CH) 2002-05-10 WO claimed
US-4819658-A Method and apparatus for measuring the temperature profile of a surface AMERICAN TELEPHONE AND TELEGRAPH COMPANY, AT&T BELL LABORATORIES (US) 1989-04-11 US claimed
US-4788436-A Radiation sensitive optical fiber and detector KOECHNER WALTER (US) 1988-11-29 US claimed
EP-0107532-B1 PLASTIC OPTICAL FIBRES, ESPECIALLY SCINTILLATING ONES, AND PROCESS FOR MAKING THEM COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1988-03-09 EP claimed
US-4552431-A Optical fibers with plastic core and polymer cladding COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1985-11-12 US claimed
US-4262202-A Scintillator detector array GENERAL ELECTRIC COMPANY (US) 1981-04-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638602-B2 Metal organic framework particles as radioisotope detectors SLCO1A2, SLCO4C1, SLCO2A1 ALOX15 4460/4885TSHR 934/4885CASP1 2302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.