Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415206 | 1.00 | LMNA (0.65) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL367133 | 0.90 | LMNA (0.68) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL15610852 | 0.88 | LMNA (0.65) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL14023821 | 0.85 | LMNA (0.62) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL14023806 | 0.85 | LMNA (0.68) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL2830638 | 0.82 | LMNA (0.73) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL15024639 | 0.81 | LMNA (0.80) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL368130 | 0.81 | LMNA (0.78) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL367605 | 0.81 | LMNA (0.62) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3915318 | 0.80 | LMNA (0.68) | LMNATHRBCYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202945-B1 | METHODS FOR PREPARING PERFLUORINATED [18 F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIV CATHOLIQUE LOUVAIN (BE) | 2005-08-17 | — | — | EP | claimed |
| EP-1202945-A1 | METHODS FOR PREPARING PERFLUORINATED [18 F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012575-A1 | METHODS FOR PREPARING PERFLUORINATED [18F]-RADIOLABELLED NITROIMIDAZOLE DERIVATIVES FOR CELLULAR HYPOXIA DETECTION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2001-02-22 | — | — | WO | claimed |
| WO-2026102212-A1 | MACROCYCLIC MCL-1 INHIBITORS | VANDERBILT UNIVERSITY (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250340519-A1 | RADIOLABELLED COMPOUND | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2025-11-06 | — | — | US | disclosed |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | GILEAD SCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4624459-A2 | RADIOLABELLED COMPOUND | Oxford University Innovation Limited (GB) | 2025-10-01 | — | — | EP | disclosed |
| CN-119679042-A | Enzymatic hydrolysis biomass feed, method for preparing feed by using edible fungus enzymatic hydrolysis biomass and application of feed | 南京高新工大生物技术研究院有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119613752-A | Preparation method for constructing supermolecular polymer gel based on reaction of column [5] arene and crown ether | 江西理工大学 | 2025-03-14 | — | — | CN | disclosed |
| US-20240398799-A1 | COMPOSITIONS AND METHODS FOR GENERATING SYNTHETIC LETHALITY IN TUMORS | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2024-12-05 | — | — | US | disclosed |
| US-6252087-B1 | COMPLEXING WITH A PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-06-26 | — | — | US | disclosed |
| US-6218179-B1 | NUCLEOTIDE SEQUENCES CODING HUMAN METALLOTHIONEIN REGULATORY SEQUENCES; FOR REDUCING ISCHEMIC INJURY TO A CELL EXPOSED TO HYPOXIC CONDITIONS | SRI INTERNATIONAL | 2001-04-17 | — | — | US | disclosed |
| US-5843404-A | Immunogenic conjugates of nitroaromatic compounds and proteins; monoclonal antibodies specific for nitroaromatic compounds , their protein conjugates | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0799308-A1 | TISSUE SPECIFIC HYPOXIA REGULATED THERAPEUTIC CONSTRUCTS | SRI INTERNATIONAL (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0669913-A4 | DETECTION OF HYPOXIA. | UNIV PENNSYLVANIA (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5540908-A | DETECTION OF OXYGEN DEPRIVATION USING IMMUNOHISTOLOGICAL METHODS | THE TRUSTEES OF THE UNIV. OF PENNSYLVANIA (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1996020276-A1 | TISSUE SPECIFIC HYPOXIA REGULATED THERAPEUTIC CONSTRUCTS | SRI INTERNATIONAL (US) | 1996-07-04 | — | — | WO | disclosed |
| EP-0669913-A1 | DETECTION OF HYPOXIA | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011348-A1 | DETECTION OF HYPOXIA | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388585-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT1, PRMT5, PRMT6 | LMNA 1373/4885THRB 1508/4885CYP2C19 4791/4885 |
| US-20250340519-A1 | RADIOLABELLED COMPOUND | PARP3, PARP2, PARP1 | LMNA 4486/4885THRB 2271/4885CYP2C19 452/4885 |
| US-12448388-B2 | PRMT5 inhibitors and uses thereof | PRMT5, PRMT1, PRMT9 | LMNA 2517/4885THRB 3384/4885CYP2C19 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.