Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111022 | 0.81 | RIPK1 (0.33) | KMT2AMEN1NPC1RAB9AHTR2A | |
| SCHEMBL29129339 | 0.78 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AHTR2A | |
| SCHEMBL5481836 | 0.75 | HTR2A (0.47) | KMT2AHTR2APOLBTSHRCYP1A2 | |
| SCHEMBL3740798 | 0.74 | HTR2A (0.39) | KMT2AMEN1HTR2APOLBTSHR | |
| SCHEMBL23525416 | 0.73 | CYP1A2 (0.35) | KMT2AMEN1HTR2AALDH1A1POLB | |
| SCHEMBL2006601 | 0.73 | FABP5 (0.46) | KMT2AFABP5FABP7 | |
| SCHEMBL23781817 | 0.72 | CASP3 (0.33) | ALDH1A1POLBTSHRCYP1A2FABP5 | |
| SCHEMBL25373589 | 0.71 | ALDH1A1 (0.41) | KMT2ANPC1RAB9AHTTL3MBTL1 | |
| SCHEMBL16242267 | 0.71 | KMT2A (0.40) | KMT2AHTR2ATSHRCYP1A2FABP5 | |
| SCHEMBL5730789 | 0.71 | MEN1 (0.37) | KMT2AMEN1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231695-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077401-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |